Breast cancer arises from a complex interplay of genetic, lifestyle, and environmental factors. Understanding these elements is crucial for assessing risk and implementing preventive measures.
🧬 Genetic Risk Factors
Approximately 5% to 10% of breast cancer cases are hereditary, stemming from mutations passed down from parents to children. Key genetic contributors include:American Cancer Society+1Breastcancer.org+1
- BRCA1 and BRCA2: Mutations in these genes significantly elevate the risk of breast and ovarian cancers.
- Other Genetic Mutations: Alterations in genes such as PALB2, ATM, CHEK2, and TP53 also increase breast cancer risk. Cancer Research UK
Additionally, having a family history of breast cancer, especially in first-degree relatives diagnosed before age 50, heightens one’s risk. Cancer Research UK